SAR sem 8

SAR Sem 8

PC_Sem 8_Major SAR_Wilson

Synthesis

Synthesis 1

Synthesis 2


Synthesis 3

ANS-Cholinergic Drugs

ANS-Cholinergic Drugs

Cholinergic Drugs
Muscarinic agonists : methacholine, carbachol, bethanechol, pilocarpine
Acetylcholine esterase inhibitors : physostigmine, neostigmine*, pyridostigmine,
edrophonium, echothiophate, malathion, parathion, paraoxonC, sarin, pralidoxime
AntiAlzheimer’s : Tacrine*, donepezil, rivastigmine
Cholinergic antagonists : Atropine, scopolamine, homatropine, ipratropium
cyclopentolate*, dicyclomine*, benztropine, procyclidine, isopropamide, tropicamide
Ganglion blockers : (Self study- 1 hr) trimethaphan, mecamylamine, hexamethonium
Neuromuscular blockers :(Self study) tubocurarine, gallamine, succinylcholine,
decamethonium

Notes

cholinergics and anticholinesterases


Drug treatment of alzheimers disease

Neuromuscular blocking agents and ganglionic blockers-converted

ANS Drugs - Adrenergic Drugs

Adrenergic Drugs

Alpha adrenergic agonists: phenylephrine*, naphazoline, xylometazoline, oxymetazoline,
methyldopa, clonidine, guanabenz, guanafacine
Beta agonists : Isoproterenol, colterol, metaproterenol, terbutaline*, albuterol,
isoxsuprine, ritodrine
Alpha antagonist : tolazoline, phentolamine, phenoxybenzamine, prazosin, doxazosin
Beta Antagonists : pronethalol, propranolol*, pindolol, sotalol, timolol, atenolol,
metoprolol, esmolol, acebutolol, carvedilol, labetalol* (last two for self study, including
synthesis of labetalol)
Other adrenergic agents (Self study-2 hrs) : amphetamine, pseudoephedrine, ephedrine,
guanethidine, propylhexedrine, reserpine


Notes

Adrenergic Synthesis And Metabolism animation

Catecholamine Biosynthesis Pathway

mechanism of action of adrenergic receptor

Antiparkinson’s

Syllabus

carbidopa, levodopa, selegiline, amantadine, benztropine, procyclidine, orphenadrine
(last 3 drugs for self study- 1 hr)

Notes Antiparkinsons drugs

Parkinson Disease animation

Parkinson's Disease, Animation

Parkinson's Disease Treatment Mode of Action Animation

COMT Inhibitors for Parkinson's Disease

Anxiolytics

Anxiolytics

Oxazepam, buspirone, meprobamate, tybamate (last two for self study- 1 hr)

Powerpoint Presentataion

Antipsychotics

Antipsychotics

Powerpoint Presentation for Topic

https://drive.google.com/file/d/1IkeiX_nijV0NaJgr3mQsoeWGupGxje3H/view?usp=sharing

Supporting files

VDOs


Psychopharmacology - Antipsychotics Pharmacology

Clera Antipsychotic Science

Schizophrenia Part 1 of 4 - Medical Animation by Watermark

Schizophrenia Part 2 of 4 - Medical Animation by Watermark

Schizophrenia Part 3 of 4 - Medical Animation by Watermark

Schizophrenia Part 4 of 4 - Medical Animation by Watermark