Wednesday, February 20, 2019

Thyroid Hormones

Thyroid gland (weighs about 30 g in adults) is located on either side of the trachea below the larynx. It produces two principal hormones thyroxin (T4; 3,5,3',5'-tetraiodothyronine) and 3,5,3'-triiodothyronine (T3)-which regulate the metabolic rate of the body. Thyroid gland also secretes calcitonin, a Hormone Concerned with calcium homeostasis.

Classification:
Inhibit Hormone Synthesis (Anti thyroid Drugs):-
¢Propylthiouracil, Methimazole, Carbimazole
Inhibit Iodide Trapping (Ionic Inhibitors):-
¢Thiocynates (-SCN), Perchlorates (-ClO4), Nitrates(-NO3)
Inhibit Hormone Release:-
¢Iodine, Iodides of Na and K, Organic Iodide
Destroy Thyroid Tissue:-
¢Radioactive Iodine (131I, 125I, 123I)
 Thyroid hormone
    (Used to treat thyroid hormone deficiency)
   Levothyroxine, also known as L-thyroxine, is a manufactured form of the thyroid hormone, thyroxine (T4)


Thyroid Hormones

Thyroid Animation

Thyroid Hormone Synthesis and Antithyroid drugs